產(chǎn)品編號：GM-77904AB
產(chǎn)品名稱：Anti-GAPDH mIgG2a Antibody
目錄價：詢價
GM-77904AB-10
GM-77904AB-100
GM-77904AB-1000
Source/Isotype Monoclonal Mouse IgG2a
Species Reactivity Human, Mouse, Canine, Rat, Pig
Conjugate Unconnjugated
Other Names G3PD, GAPD, GAPDH, OK/SW cl.12
Application Western blotting: 1:1000-1:5000; WB-Quality tested
Background GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. One of the GAPDH moonlighting function is its role in adhesion and binding to other partners. GAPDH can itself activate transcription. GAPDH acts as a reversible metabolic switch under oxidative stress. GAPDH also appears to be involved in the vesicle transport from the endoplasmic reticulum (ER) to the Golgi apparatus which is part of shipping route for secreted proteins. Because the GAPDH gene is often stably and constitutively expressed at high levels in most tissues and cells, it is considered a housekeeping gene. For this reason, GAPDH is commonly used by biological researchers as a loading control for western blot and as a control for qPCR.
Formulation 20mM Histine, 50% glycerinum, 0.05% Bacteriostatic preservative, pH 6.0.
產(chǎn)品編號：GM-77904AB
產(chǎn)品名稱：Anti-GAPDH mIgG2a Antibody
目錄價：詢價
GM-77904AB-10
GM-77904AB-100
GM-77904AB-1000
Source/Isotype Monoclonal Mouse IgG2a
Species Reactivity Human, Mouse, Canine, Rat, Pig
Conjugate Unconnjugated
Other Names G3PD, GAPD, GAPDH, OK/SW cl.12
Application Western blotting: 1:1000-1:5000; WB-Quality tested
Background GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. One of the GAPDH moonlighting function is its role in adhesion and binding to other partners. GAPDH can itself activate transcription. GAPDH acts as a reversible metabolic switch under oxidative stress. GAPDH also appears to be involved in the vesicle transport from the endoplasmic reticulum (ER) to the Golgi apparatus which is part of shipping route for secreted proteins. Because the GAPDH gene is often stably and constitutively expressed at high levels in most tissues and cells, it is considered a housekeeping gene. For this reason, GAPDH is commonly used by biological researchers as a loading control for western blot and as a control for qPCR.
Formulation 20mM Histine, 50% glycerinum, 0.05% Bacteriostatic preservative, pH 6.0.
